Сведения о компании

  • Organic Herb Inc.

  •  [Hunan,China]
  • Деловой Тип :производитель
  • Main Mark: Африка , Северные и Южная Америка , Азия , карибский , Восточная Европа , Европа , средний Восток , Северная Европа , Океания , Другие рынки , Западная Европа , Мировой
  • Экспортер:91% - 100%
  • Certs:ISO9001, FDA
  • Описание:Rosemary Extract Powder,Carnosic Acid Powder,Rosmarinic Acid Extract
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Organic Herb Inc.

Rosemary Extract Powder,Carnosic Acid Powder,Rosmarinic Acid Extract

Rosemary+Leaf+Extract+Carnosic+Acid+Powder

Поделиться с:  
    Вид оплаты: L/C,T/T,D/P,Western Union
    Incoterm: FOB,CIF,FCA
    Количество минимального заказа: 1 Bag/Bags
    Срок поставки: 7 дней

Базовая информация

Модель: 60%

Сырье: растения

Appearance: Yellow Powder

Specfication: 60%

Test Method: HPLC

Latin Name: Rosemary

Additional Info

Подробности Упаковки: Drum, Plastic Container, Vacuum Packed, OEM Services Provide

производительность: 30 Ton per Month

марка: OHI

транспорт: Ocean,Land,Air

Место происхождения: China

Способность поставки: 30 Ton per Month

Сертификаты : HACCP,ISO, Halal, Kosher

Описание продукта

%3Ch2%3E+%3Cb%3ERosemary+Extract+Carnosic+acid%3C%2Fb%3E+%3C%2Fh2%3E+%3Cp+class%3D%22MsoNormal%22+style%3D%22text-indent%3A21.0pt%3B%22%3E+Name+%3A+Rosemary+Extract+Carnosic+acid+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22+style%3D%22text-indent%3A21.0pt%3B%22%3E+Source%3A+Rosemary+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22+style%3D%22text-indent%3A21.0pt%3B%22%3E+Botanical+Name+%3A+Rosmarinus+officinalis+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22+style%3D%22text-indent%3A21.0pt%3B%22%3E+Extract+part%3A+Leaf+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22+style%3D%22text-indent%3A21.0pt%3B%22%3E+Composition+%3A+Carnosic+acid+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22+style%3D%22text-indent%3A21.0pt%3B%22%3E+Purity%3A60%25+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22+style%3D%22text-indent%3A21.0pt%3B%22%3E+Appearance%3A+Fine+Brownish+Yellow+powder+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22+style%3D%22text-indent%3A21.0pt%3B%22%3E+Country+of+origin%3AP.R.+China+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22+style%3D%22text-indent%3A21.0pt%3B%22%3E+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+%3Cb%3ESource+%3C%2Fb%3E+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+Rosmarinus+officinalis+L.+from+Lamiaceae+family%2C+is+commonly+known+as+rosemary.+Rosemary+is+a+widely+cultivated+herbal+plant+that+is+originated+in+the+Mediterranean+area.+Rosemary+is+an+aromatic+evergreen+shrub+with+leaves+similar+to+%3Ca+href%3D%22https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FTsuga%22+title%3D%22Tsuga%22%3Ehemlock%3C%2Fa%3E+needles+.The+leaves+are+used+as+a+flavoring+in+foods+and+a+prescription+for+treating+minor+ailments+including+%3Agout%2C+cough%2C+headache%2C+high+blood+pressure%2C+and+reducing+age-related+memory+loss.+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+Rosemary+is+used+topically+for+preventing+and+treating+baldness+by+applying+to+the+skin+%3B+and+treating+circulation+problems%2C+toothache%2C+a+skin+condition+called+eczema%2C+and+joint+or+muscle+pain+such+as+myalgia%2C+sciatica%2C+and+intercostal+neuralgia.+It+is+also+used+for+wound+healing%2C+in+bath+therapy+%28balneotherapy%29%2C+and+as+an+insect+repellent.+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+%3Cstrong%3EMain+Bio-actives%3C%2Fstrong%3E+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22+align%3D%22left%22%3E+Rosemary+contains+a+number+of+phytochemicals%2C+including+rosmarinic+acid%2C+camphor%2C+caffeic+acid%2C+ursolic+acid%2C+betulinic+acid%2C+rosmanol+and+the+antioxidants+carnosic+acid+and+carnosol.+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22+align%3D%22left%22%3E+Rosmarinic+acid+is+a+chemical+compound+firstly+found+in+Rosmarinus+officinalis+which+has+antioxidant+properties.+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+Another+main+antioxidant+in+rosemary+is+the+phenolic+diterpene+carnosic+acid+%2Cappears+to+be+the+main+substance+for+general+oxidation+leading+to+artifacts+with%CE%B3-or+%CE%B4-lactone+structure+in+extracts+of+Rosmarinus+officinalis+.+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+Rosmarinic+acid+is+a+caffeic+acid+ester+of+salvianic+acid+A+that+acts+as+a+GABA+transaminase+inhibitor%2C+more+specifically+on+4-aminobutyrate+transaminase.Rosmarinic+acid+also+inhibits+the+expression+of+indoleamine+2%2C3-dioxygenase+via+its+cyclooxygenase-inhibiting+properties.+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+%3Cstrong%3EFunctions%3C%2Fstrong%3E+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+%3Cstrong%3EAntioxidant%3C%2Fstrong%3E+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22+align%3D%22left%22%3E+Constituents+in+Rosemary+extracts+from+Rosmarinus+officinalis+L+contains+several+compounds+proven+to+have+antioxidative+function.Early+investigation+proved+that+carnosol+and+carnosic+acid+have+been+suggested+to+account+for+over+90%25+of+the+antioxidant+properties+of+rosemary+extract.Purified+carnosol+and+carnosic+acid+are+powerful+inhibitors+of+lipid+peroxidation+in+microsomal+and+liposomal+systems%2C+more+effective+than+propyl+gallate.Carnosol+and+carnosic+acid+are+good+scavengers+of+peroxyl+radicals+%28CCl3O2%29+generated+by+pulse+radiolysis%2C+with+calculated+rate+constants+of+1%E2%80%933+%C3%97+106M-1+S-1+and+2.7+%C3%97+107M-1+S-1+respectively.Carnosic+acid+reacted+with+HOCl+in+such+a+way+as+to+protect+the+protein+%CE%B11-antiproteinase+against+inactivationand+appears+to+scavenge+H2O2%2C+but+it+could+also+act+as+a+substrate+for+the+peroxidase+system.Both+carnosol+and+carnosic+acid+stimulated+DNA+damage+in+the+bleomycin+assay+but+they+scavenged+hydroxyl+radicals+in+the+deoxyribose+assay.+The+calculated+rate+constants+for+reaction+with+%C2%B7OH+in+the+deoxyribose+system+for+carnosol+and+carnosic+acid+were+8.7+%C3%97+1010M-1+and+5.9+%C3%97+1010M-1+S-1respectively.Moreover+they+also+reduce+cytochrome+c+but+with+a+rate+constant+significantly+lower+than+that+of+O-.2.+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+%3Cstrong%3EAnti-inflammatory%3C%2Fstrong%3E+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+Biosci+Biotechnol+Biochem.+reported+in+2007+supercritical+fluid+SF-CO2+treatment+of+Rosemarinus+officinalis+L.+fresh+leaves+under+optimum+conditions+%2880+degrees+C+at+5%2C000+psi%29+yielded+5.3%25+of+extract+supercritical+fluid+extraction+%28SFE%29-80%2C+in+which+five+major+active+principles+were+identified+by+liquid+chromatography%2Fmass+spectrometry+%28LC%2FMS%29%2C+viz.%2C+rosmarinic+acid%2C+carnosol%2C+12-methoxycarnosic+acid%2C+carnosic+acid%2C+and+methyl+carnosate.+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+When+treated+in+RAW+264.7%2C+apparent+dose-dependent+NO+inhibition.+SFE-80+exhibited+dose-dependent+viability+suppression+and+significant+tumor+necrosis+factor+alpha+%28TNF-alpha%29+production+in+Hep+3B%2C+whereas+no+effect+was+found+in+Chang+liver+cells.+Furthermore%2C+no+effect+was+observed+in+RAW+264.7+at+dosages+of+3.13+to+25+microg%2Fml%2C+indicating+that+SFE-80+exhibited+a+noncytotoxic+character.+Conclusively%2C+rosemary+can+be+considered+an+herbal+anti-inflammatory+and+anti-tumor+agent.+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+%3Cstrong%3EAnticancer%3C%2Fstrong%3E+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+Carnosic+acid%2C+a+phenolic+diterpene%2C+exhibited+potent+antioxidant+and+anticancer+properties+in+both+in+vivo+and+in+vitro+conditions+.Recent+research+examined+whether+carnosic+acid+could+sensitize+TRAIL-mediated+apoptosis+in+human+renal+carcinoma+Caki+cells.Research+found+that+carnosic+acid+markedly+induced+TRAIL-mediated+apoptosis+in+human+renal+carcinoma+%28Caki%2C+ACHN%2C+and+A498%29%2C+and+human+hepatocellular+carcinoma+%28SK-HEP-1%29%2C+and+human+breast+carcinoma+%28MDA-MB-231%29+cells%2C+but+not+normal+cells+%28TMCK-1+and+HSF%29.+Carnosic+acid+induced+down-regulation+of+c-FLIP+and+Bcl-2+expression+at+the+post-translational+levels%2C+and+the+over-expression+of+c-FLIP+and+Bcl-2+markedly+blocked+carnosic+acid-induced+TRAIL+sensitization.+Furthermore%2C+carnosic+acid+induced+death+receptor+%28DR%295%2C+Bcl-2+interacting+mediator+of+cell+death+%28Bim%29%2C+and+p53+up-regulated+modulator+of+apoptosis+%28PUMA%29+expression+at+the+transcriptional+levels+via+CCAAT%2Fenhancer-binding+protein-homologous+protein+%28CHOP%29.+Down-regulation+of+CHOP+expression+by+siRNA+inhibited+DR5%2C+Bim%2C+and+PUMA+expression%2C+and+attenuated+carnosic+acid+plus+TRAIL-induced+apoptosis.In+conclusion%2Cstudy+demonstrates+that+carnosic+acid+enhances+sensitization+against+TRAIL-mediated+apoptosis+through+the+down-regulation+of+c-FLIP+and+Bcl-2+expression%2C+and+up-regulation+of+ER+stress-mediated+DR5%2C+Bim%2C+and+PUMA+expression+at+the+transcriptional+levels.+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+%3Cstrong%3EAntiviral+activity%3C%2Fstrong%3E+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+Study+on+Human+respiratory+syncytial+virus+%28hRSV%29+revealed+the+bioactive+constituent+of+an+extract+of+%3Cem%3ERosmarinus+officinalis%2C%3C%2Fem%3Ecarnosic+acid+%2C+exerted+a+strong+inhibitory+effect+against+hRSV+infection.+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+Among+the+tested+bioactive+constituents+of+%3Cem%3ER.+officinalis%3C%2Fem%3E%2C+carnosic+acid+displayed+the+most+potent+anti-hRSV+activity+and+was+effective+against+both+A-+and+B-type+viruses.+Carnosic+acid+efficiently+suppressed+the+replication+of+hRSV+in+a+concentration-dependent+manner.+Carnosic+acid+effectively+suppressed+viral+gene+expression+without+inducing+type-I+interferon+production+or+affecting+cell+viability%2C+suggesting+that+it+may+directly+affect+viral+factors.+A+time+course+analysis+showed+that+addition+of+carnosic+acid+8+hours+after+infection+still+effectively+blocked+the+expression+of+hRSV+genes%2C+further+suggesting+that+carnosic+acid+directly+inhibited+the+replication+of+hRSV.+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+%3Cstrong%3ENeuroprotective%3C%2Fstrong%3E+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+The+importance+of+free+radical-induced+oxidative+damage+after+traumatic+brain+injury+%28TBI%29+has+been+well+documented.+Despite+multiple+clinical+trials+with+radical-scavenging+antioxidants+that+are+neuroprotective+in+TBI+models%2C+none+is+approved+for+acute+TBI+patients.+As+an+alternative+antioxidant+target%2C+Nrf2+is+a+transcription+factor+that+activates+expression+of+antioxidant+and+cytoprotective+genes+by+binding+to+antioxidant+response+elements+%28ARE%29+within+DNA.Researchers+hypothesized+that+administration+of+carnosic+acid+%28CA%29+would+reduce+oxidative+damage+biomarkers+in+brain+tissue+and+also+preserve+cortical+mitochondrial+respiratory+function+post-TBI.+A+mouse+controlled+cortical+impact+%28CCI%29+model+was+employed+with+a+1.0mm+cortical+deformation+injury.+Administration+of+CA+at+15+minutes+post-TBI+reduced+cortical+lipid+peroxidation%2C+protein+nitration%2C+and+cytoskeletal+breakdown+markers+in+a+dose-dependent+manner+at+48+hours+post-injury.+Moreover%2C+CA+preserved+mitochondrial+respiratory+function+compared+to+vehicle+animals.+This+was+accompanied+by+decreased+oxidative+damage+to+mitochondrial+proteins%2C+suggesting+the+mechanistic+connection+of+the+two+effects.+Lastly%2C+delaying+the+initial+administration+of+CA+up+to+8+hours+post-TBI+was+still+capable+of+reducing+cytoskeletal+breakdown%2C+thereby+demonstrating+a+clinically+relevant+therapeutic+window+for+this+approach.+This+study+demonstrates+that+pharmacological+Nrf2-ARE+induction+is+capable+of+neuroprotective+efficacy+when+administered+after+TBI.+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+%3Cbr+%2F%3E+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+%3Cb%3EApplications+%3C%2Fb%3E+%3C%2Fp%3E+%3Cp+class%3D%22MsoNormal%22%3E+Carnosic+acid+is+known+to+has+multiple+potent+biochemical+activities+including+antioxidant%2Cantiviral+%2Canticancer+and+anti-inflammatory.Researches+suggested+that+Carnosic+acid+has+potential+application+in+medical+treatment+.+%3C%2Fp%3E+%3Cp%3E+%3Cbr+%2F%3E+%3C%2Fp%3E+%3Ch2%3E+%3Cimg+src%3D%22%25oss_domain%25product%2F01%2Fc0%2F68%2F83c376396cb1643291c1c00e98.jpg%40watermark%3D2%26color%3DI0ZGRkZGRg%253D%253D%26type%3DZHJvaWRzYW5zZmFsbGJhY2s%253D%26size%3D20%26p%3D9%26t%3D80%26text%3DcnUub3JnYW5pYy1leHRyYWN0cy5jb20%3D%22+title%3D%22%22+alt%3D%22%22+%2F%3E+%3C%2Fh2%3E+%3Cp%3E+%3Cimg+src%3D%22%25oss_domain%25product%2F52%2F75%2Fea%2F02106676d9f3f37542b6f9023b.jpg%40watermark%3D2%26color%3DI0ZGRkZGRg%253D%253D%26type%3DZHJvaWRzYW5zZmFsbGJhY2s%253D%26size%3D20%26p%3D9%26t%3D80%26text%3DcnUub3JnYW5pYy1leHRyYWN0cy5jb20%3D%22+title%3D%22%22+alt%3D%22%22+%2F%3E+%3C%2Fp%3E

Группа Продуктов : Стандартные растительные экстракты

изображение Продукта
  • Rosemary+Leaf+Extract+Carnosic+Acid+Powder
  • Rosemary+Leaf+Extract+Carnosic+Acid+Powder
  • Rosemary+Leaf+Extract+Carnosic+Acid+Powder
  • Rosemary+Leaf+Extract+Carnosic+Acid+Powder
  • Rosemary+Leaf+Extract+Carnosic+Acid+Powder
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